Anxiety and depression affects nearly 1 in 5 of the population. Feelings of hopelessness, trouble sleeping and living in constant worry are all symptoms that plague millions of silent sufferers every day.

Anti-anxiety and anti-depression medications can cause serious side effects such as drowsiness, dizziness, nausea, vomiting and weight gain.

This is where serotonin supplements come in. Serotonin is a neurotransmitter that greatly affects your mood, appetite and sleep habits.

Tranquilene Review

Serotonin supplements like Tranquilene Total Calm work by increasing serotonin levels through herbs, vitamins, minerals and amino acids, beating anxiety and depression naturally.

Tranquilene Total Calm is an herbal anxiety relief containing all the key ingredients to target deficiencies in your body that can impact your mood.

Tranquilene Ingredients

With any type of stress supplement, the ingredients are the most important thing to consider. Tranquilene has a list of natural ingredients that have been shown to help with stress and anxiety.


A calcium deficiency can masquerade as anxiety and exacerbate the symptoms of those already suffering from anxiety. Calcium is vital for healthy brain function, so a calcium deficiency often leads to increased moodiness, anxiety and even panic attacks.

Calcium deficiency affects your overall sense of well-being and can alter your behavior. Low calcium levels also mimic many of the symptoms of anxiety such as cramping, lethargy, heart palpitations and a tingling in fingers and toes.

Tranquilene Ingredients

Tranquilene Total Calm contains 21mg of calcium, helping to thwart a possible calcium deficiency, thereby treating anxiety at its possible root.


Recent studies have shown that many people are deficient in magnesium. Magnesium plays a big role in over 300 different chemical reactions in the body, including nerve and blood health.

Low magnesium levels have been shown to increase anxiety symptoms such as panic attacks and contribute to many mental health problems like depression. Magnesium has also been shown to help with insomnia.

Unfortunately, magnesium also competes with calcium for absorption so taking too much of one of these minerals can lead to a deficiency in the other. Tranquilene Total Calm contains 15mg of magnesium, to combat these problems.


GABA is an amino acid known as Gamma-Amino Butyric Acid, which acts as a neurotransmitter in the central nervous system. It has a calming affect on nerves due to its ability to inhibit nerve transmissions to the brain.

For this reason, it has often been touted as a natural tranquilizer and anxiety relief. GABA provides great calming and relaxation effects that can help with symptoms of anxiety. Tranquilene Total Calm includes GABA in their proprietary blend to treat anxiety at a neural level.


Ashwagandha root has been used for thousands of years to soothe an anxious mind, treat insomnia and aid with relaxation. Ashwagandha has been commonly used by Ayurvedic healers who practice a system of traditional health care that emphasizes the relationship between the body, mind and spirit.

It has been shown to boost the immune system, elevate mood, fight panic attacks, alleviate insomnia and help the body adapt to stress. It's no wonder that Tranquilene Total Calm uses this revered root in their proprietary blend of ingredients to reduce anxiety and depression.


L-Theanine is an amino acid that is commonly found in high-quality green and black teas. In fact, it's one of the key beneficial effects associated with regular drinking of green teas.

L-Theanine has access to the central nervous system and can increase the brain's alpha waves to help people feel calmer. L-Theanine has been shown to affect your mental abilities, including the speed in which you think, your perception of the world and your mood.

This amino acid increases dopamine levels, reduce stress and negative responses to stress, and increase feelings of relaxation. It also increases serotonin levels, which is why it's a key ingredient in Tranquilene Total Calm's proprietary blend.

Benefits of Tranquilene

  • Anxiety Relief: Tranquilene Total Calm is designed to boost serotonin levels and reduce feelings of anxiety naturally. The amazing blend of 15 ingredients helps to increase the production of serotonin, which leaves you feeling happier, relaxed and more confident. The combination of herbs, minerals, vitamins and amino acids also help to target nutritional deficiencies, which can exacerbate feelings of anxiety.
  • Healthy Cognitive Functions: Anxiety and stress can have a negative impact on your cognitive functions, including memory, concentration, ability to focus and speed of thought. Boosting your serotonin levels through Tranquilene Total Calm restores healthy brain functions allowing you to get the most out of your work and home life.
  • Reduce Insomnia: The proprietary blend of ingredients in Tranquilene Total Calm aids in a restful night's sleep. Insomnia and other sleep disorders have long been a common symptom of low serotonin levels. This supplement boosts serotonin, naturally increasing feelings of sleepiness, which combat insomnia caused by anxiety and depression.

Drawbacks of Tranquilene

As with any herbal remedy, it can take some time for Tranquilene Total Calm to take effect. Some people notice results almost instantly, while other may not notice a big difference for several weeks. However, this is due to the all-natural nature of the ingredients and though it may take some time, you should notice a gradual improvement in anxiety levels from the first week.

Tranquilene Total Calm is not designed to completely replace anti-anxiety drugs and those suffering from very severe anxiety and depression may need much stronger medication to see improvements in their mental health. However, for people suffering from mild to moderate anxiety, this supplement works brilliantly and effectively to combat stress, anxiety and insomnia.

Is Tranquilene Safe?

The good thing about Tranquilene is it's packed with the natural ingredients I mentioned above. Also, there has been a ton of clinical research on Tranquilene's active ingredients.


I found Tranquilene Total Calm to be an excellent serotonin supplement for reducing feelings of anxiety. Within four days of taking this supplement, I noticed improvements in my mood and that I was less stressed about things that normally would have seriously affected me.

I'm also sleeping much better than before and haven't been plagued all night with anxious thoughts, a benefit I hadn't even anticipated but has been an amazing bonus. I would definitely recommend this supplement for anyone looking for a natural way to improve their anxiety.